Revolusi Teknik Radioterapi pada Karsinoma Nasofaring

Aurika Sinambela, Nana Supriana

Sari


Karsinoma nasofaring (KNF) adalah keganasan yang berasal dari sel epitel nasofaring. Laju insidens paling tinggi ada di Asia Tenggara, termasuk Indonesia.Perkembangan terapi radiasi menjadi revolusi tatalaksana KNF.Dalam beberapa dekade terakhir, akumulasi pengetahuan mengenai radiobiologi dan penentuan volume target, serta modalitas radiodiagnostik yang semakin maju memungkinkan revolusi teknik radiasi KNF.Peningkatan signifikan sintasan dan pengurangan toksisitas yang fatal pada terapi radiasi pasien KNF dapat dicapai setelah revolusi teknik radiasi dari era 2DRT, 3DCRT, hingga IMRT.


Kata Kunci


Karsinoma nasofaring, radiasi, 2DRT, 3DCRT, IMRT

Teks Lengkap:

PDF

Referensi


Ma J, Cao S. The Epidemiology of Nasopharyngeal Carcinoma. In: Lu J, Cooper J, Lee A, editors. Nasopharyngeal Cancer Multidisciplinary Management. Berlin: Springer-Verlag Berlin Heidelberg; 2010. p. 1–7.

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-tieulent J, Jemal A. Global Cancer Statistics, 2012. CA a cancer J Clin [Internet]. 2015;65(2):87–108. Available from: http://onlinelibrary.wiley.com/doi/10.3322/caac.21262/abstract

Halperin E, Wazer D, Perez C. The Discipline of Radiation Oncology. In: Halperin E, Wazer D, Perez C, editors. Perez and Brady’s Principles and Practice of Radiation Oncology. 6th ed. Philadelphia: Lippincot Williams & Wilkins; 2013. p. 2–275.

Lee AWM, Sze WM, Au JSK, Leung SF, Leung TW, Chua DTT, et al. Treatment results for nasopharyngeal carcinoma in the modern era: The Hong Kong experience. Int J Radiat Oncol Biol Phys. 2005;61(4):1107–16.

Lok B, Setto J, Ho F, Rias N. Nasopharynx. In: Halperin E, Wazer D, Perez C, Brady L, editors. Perez and Brady’s Principles and Practice of Radiation Oncology. 6th ed. Philadelphia: Lippincot Williams & Wilkins; 2013. p. 730–60.

Lu J, Kong L, Lee N. Nasopharyngeal Carcinoma. In: Lu J, Brady L, editors. Decision Making in Radiation Oncology Volume 1. New York: Springer-Verlag Heidelberg Dodrecht; 2011. p. 45–74.

Lee N, Laufer M, Ove R, Foote RL, Bonner JA. Nasopharyngeal Carcinoma. In: Gunderson LL, Tepper JE, editors. Clinical Radiation Oncology. 3rd ed. Philadelphia: Elsevier; 2000. p. 618–38.

Carioli G, Negri E, Kawakita D, Garavello W, La Vecchia C, Malvezzi M. Global trends in nasopharyngeal cancer mortality since 1970 and predictions for 2020: Focus on low-risk areas. Int J Cancer. 2017;140(10):2256–64.

National Comprehensive Cancer Network. NCCN Guidelines: Head and Neck Cancers version 1. 2017.

Riaz N, Tam M, Lee N. Nasopharyngeal Carcinoma. In: Brady LW, Combs SE, Lu JJ, editors. Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy. Switzerland: Springer; 2015. p. 3–16.

American Joint Commitee on Cancer. AJCC cancer staging atlas: a companion to the 7th editions of AJCC cancer staging manual and handbook. 2nd ed. New York: Springer; 2012.

Lee AW, Lydiatt WM, Colevas AD, Glastonbury CM, Le QTX, O’Sullivan B, et al. AJCC Cancer Staging Manual. 8th ed. Amin MB, editor. Chicago: Springer; 2017. 103-112 p.

Ouyang PY, Su Z, Ma XH, Mao YP, Liu MZ, Xie FY. Comparison of TNM staging systems for nasopharyngeal carcinoma, and proposal of a new staging system. Br J Cancer. 2013;109(12):2987–97.

Pan JJ, Ng WT, Zong JF, Chan LLK, O’Sullivan B, Lin SJ, et al. Proposal for the 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer. 2016;122(4):546–58.

Zong J, Lin S, Lin J, Tang L, Chen B, Zhang M, et al. Impact of intensity-modulated radiotherapy on nasopharyngeal carcinoma: Validation of the 7th edition AJCC staging system. Oral Oncol [Internet]. 2015;51(3):254–9. Available from: http://dx.doi.org/10.1016/j.oraloncology.2014.10.012

Chiu KC, Leung SW, Weng HH, Cheng YF, Lee TY, Lee RJ, et al. A comparison of staging systems for nasopharyngeal carcinoma in Taiwan. Chinese J Radiol. 2003;28(3):131–5.

Lee AWM, Ng WT, Chan LK, Chan OSH, Hung WM, Chan CC, et al. The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement. Oral Oncol. 2012;48(10):1007–13.

Lee AWM, Ng WT, Chan LLK, Hung WM, Chan CCC, Sze HCK, et al. Evolution of treatment for nasopharyngeal cancer - Success and setback in the intensity-modulated radiotherapy era. Radiother Oncol [Internet]. 2014;110(3):377–84. Available from: http://dx.doi.org/10.1016/j.radonc.2014.02.003

Thariat J, Hannoun-Levi J-M, Sun Myint A, Vuong T, Gérard J-P. Past, present, and future of radiotherapy for the benefit of patients. Nat Rev Clin Oncol [Internet]. 2012;10(1):52–60. Available from: http://www.nature.com/doifinder/10.1038/nrclinonc.2012.203

GB N. Syndrome of malignant tumors of the nasopharynx: A report of 79 cases. JAMA. 1922;79:10–4.

Mekie D, Lawley M. Nasopharyngeal carcinoma. Arch Surg. 1954;69:841–8.

Wolden SL, Zelefsky MJ, Hunt MA, Rosenzweig KE, Chong LM, Kraus DH, et al. Failure of a 3D conformal boost to improve radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2001;49(5):1229–34.

Teo PML, Leung SF, Tung SY, Zee B, Sham JST, Lee AWM, et al. Dose-response relationship of nasopharyngeal carcinoma above conventional tumoricidal level: A study by the Hong Kong nasopharyngeal carcinoma study group (HKNPCSG). Radiother Oncol. 2006;79(1):27–33.

Ho JHC. An Epidemiologic and Clinical Study of Nasopharyngeal Carcinoma. Radiat Oncol Biol Phys. 1978;4(3 and 4):183–98.

Licitra L, Bernier J, Cvitkovic E, Grandi C, Spinazz?? S, Bruzzi P, et al. Cancer of the nasopharynx. Crit Rev Oncol Hematol. 2003;45(2):199–214.

Dobbs J, Barret A, Ash D. Nasopharynx. In: Practical Radiotherapy Planning. 2nd ed. London: Edward Arnold; 1992. p. 55–61.

Kam MKM, Chau RMC, Suen J, Choi PHK, Teo PML. Intensity-modulated radiotherapy in nasopharyngeal carcinoma: Dosimetric advantage over conventional plans and feasibility of dose escalation. Int J Radiat Oncol Biol Phys. 2003;56(1):145–57.

Leibel SA, Kutcher GJ, Harrison LB, Fass DE, Burman CM, Hunt MA, et al. Improved dose distributions for 3d conformal boost treatments in carcinoma of the nasopharynx. Int J Radiat Oncol Biol Phys. 1991;20(4):823–33.

Teo PML, Ma BBY, Chan ATC. Radiotherapy for nasopharyngeal carcinoma - Transition from two-dimensional to three-dimensional methods. Radiother Oncol. 2004;73(2):163–72.

Lai S-Z, Li W-F, Chen L, Luo W, Chen Y-Y, Liu L-Z, et al. How Does Intensity-Modulated Radiotherapy Versus Conventional Two-Dimensional Radiotherapy Influence the Treatment Results in Nasopharyngeal Carcinoma Patients? Int J Radiat Oncol [Internet]. 2011;80(3):661–8. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0360301610004591

Amornmarn R, Prempree T, Sewchand W, Jaiwatana J. Radiation management of advanced nasopharyngeal cancer. Cancer. 1983;52(5):802–7.

Rosenblatt E, Abdel-Wahab M, El-Gantiry M, Elattar I, Bourque JM, Afiane M, et al. Brachytherapy boost in loco-regionally advanced nasopharyngeal carcinoma: a prospective randomized trial of the International Atomic Energy Agency. Radiat Oncol. 2014;9:67.

Kovács G, Martinez-Monge R, Budrukkar A, Guinot JL, Johansson B, Strnad V, et al. GEC-ESTRO ACROP recommendations for head & neck brachytherapy in squamous cell carcinomas: 1st update – Improvement by cross sectional imaging based treatment planning and stepping source technology. Radiother Oncol. 2017;122(2):248–54.

Mazeron J-J, Ardiet J-M, Haie-Méder C, Kovács G, Levendag P, Peiffert D, et al. GEC-ESTRO recommendations for brachytherapy for head and neck squamous cell carcinomas. Radiother Oncol [Internet]. 2009;91(2):150–6. Available from: http://linkinghub.elsevier.com/retrieve/pii/S016781400900019X

Cheng G, Han D, Wang J. Application of Brachytherapy for Recurrent Nasopharyngeal Carcinoma After Chemoradiation Therapy. Int J Radiat Oncol [Internet]. 2017;99(2):E329. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0360301617324410

Moretto F, Rampino M, Munoz F, Ruo Redda MG, Reali A, Balcet V, et al. Conventional 2D (2DRT) and 3D conformal radiotherapy (3DCRT) versus intensity-modulated radiotherapy (IMRT) for nasopharyngeal cancer treatment. Radiol Med. 2014;119(8):634–41.

Tejpal G, JaiPrakash A, Susovan B, Ghosh-Laskar S, Murthy V, Budrukkar A. IMRT and IGRT in head and neck cancer: Have we delivered what we promised? Indian J Surg Oncol. 2010;1(2):166–85.

RSCM DR. Sejarah Perkembangan Radioterapi. 2016 Nov;(November).




DOI: https://doi.org/10.32532/jori.v9i1.71 <

Article metrics

Abstract views : 2421 | views : 2606

Refbacks

  • Saat ini tidak ada refbacks.




  

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.